What is Fat Tolerance Test
Fat Tolerance Test is the determination of Postprandial Triglyceride levels after consumption of a standardized meal.
More specifically, Fat Tolerance Test is the determination of the triglyceride levels 4hours after the consumption of a standardized meal, containing 75g saturated fat, 25g carbohydrate and 10g protein.
The determination of postprandial triglyceride levels is very important because - as already mentioned in the previous section - the determination of fasting triglyceride levels cannot predict the postprandial lipid status since it takes place after many hours of fasting.
The need to determine the postprandial triglyceride levels is supported by many clinical studies such as the Women's Health Study, the Copenhagen City Heart Study, the Physicians Health Study, the Apolipoprotein-related Mortality Risk Study, the second Northwick Park Heart Study, the Norwegian Study and the ARIC study.
For postprandial triglyceride levels, until recently, there was no agreement. However, the group of experts, after a meta-analysis of 113 studies published in September 2011, standardized the way of determining and evaluating the postprandial triglyceride levels.
The method of determination and evaluation of postprandial triglyceride levels was defined upon the approvement of the Fat Tolerance Test. The measurement of postprandial triglyceride levels should be performed at a specific time after consuming a standardized amount of food.
The Fat Tolerance Test is performed as follows:
• We administer to the patient, after 12 hours of fasting, a standardized meal containing 75g saturated fat, 25g carbohydrate and 10g protein.
• 4 hours after the end of the meal, we take blood sample for triglyceride levels determination.
• If the value is > 220 mg / dL, then the test is positive.
The LIPOTEST-meal is the standard meal for the Fat Tolerance Test.
It is recognized-authorized by the EOF and it is under patent filling in its commercial form by the company D.GENOMERES Medical Research.
It is the only meal worldwide used to perform the Fat Tolerance Test.